Experts back statin prescriptions

Patients who are prescribed statins should continue to take them, experts have said

Patients who are prescribed statins should continue to take them, experts have said

First published in National News © by

Drugs currently used to lower cholesterol offer greater benefits than side-effects, experts have said.

The Medicines and Healthcare products Regulatory Agency (MHRA) said patients who are prescribed statins should continue to take them, despite articles in the British Medical Journal (BMJ) earlier this year that they could cause harmful side-effects and did not cut death rates.

The MHRA's monthly Drug Safety Update today said latest evidence from large clinical trials has shown statins can save lives by reducing the risk of heart attacks, strokes and the need for heart surgery.

Statins are commonly prescribed for people at risk of heart attack because of their cholesterol-reducing properties, with as many as seven million patients thought to be using them regularly in the UK.

But scientists have signalled they also have anti-inflammatory effects.

And earlier this month the BMJ said it was setting up a panel of experts to decide whether it should completely retract two articles which suggested the drugs presented the risk of serious side-effects without a realistic prospect of cutting death rates .

The papers prompted a row, with one expert calling them ''misleading''.

Writing in the Drug Safety Update today, the MHRA said most side-effects experienced by people who take statins are mild and muscle-related problems are the most frequently reported issues. The product information lists advice about how to use statins and any potential side-effects, it said.

Dr June Raine, the MHRA's director of vigilance and risk management of medicines, said p eople should continue to take their statins as prescribed.

She said: "Large clinical trials have shown that statins can save lives by reducing the risk of heart attacks, strokes and the need for heart surgery.

"The MHRA continually reviews the information on the safety of statins. We will update the prescribing advice for statins in light of any substantial new evidence of safety concerns.

"If patients have any concerns about their medicines then they should speak to their doctor."

She said anyone suspected to be experiencing side-effects should report it to the MHRA through the Yellow Card Scheme, used to collect information on drugs from the client and medical professionals, at www.yellowcard.mhra.gov.uk.

Statins are a group of medicines that specifically target so-called "bad cholesterol" in the blood.

People can lower their risk naturally by eating a healthy diet, low in saturated fats, and increasing the amount of omega 3 fatty acids.

The NHS estimates that statins save 7,000 lives a year in the UK.

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