Uncapped Southampton left-back Luke Shaw has been called up to the England squad for next Wednesday's friendly against Denmark.
Shaw, 18, has been named as part of a 30-man squad for the game at Wembley.
Fellow left-backs Ashley Cole and Leighton Baines have also been included.
Cardiff defender Steven Caulker has been called up in place of injured Manchester United man Phil Jones.
Shaw's Southampton colleagues Adam Lallana and Jay Rodriguez retain their places while Jermain Defoe is included following his move to Toronto FC.
Raheem Sterling, Alex Oxlade-Chamberlain and Andros Townsend make the 30 but there is no place for in-form Sunderland winger Adam Johnson.
Andy Carroll has also been overlooked despite his recovery from a serious foot injury. Hodgson has opted to pick Saints' Rickie Lambert ahead of the West Ham man.
Hodgson has named four goalkeepers for the friendly - Joe Hart, fit-again Ben Foster, Fraser Forster and John Ruddy.
The game will be the last the Three Lions play before Hodgson selects his World Cup squad.
Stoke goalkeeper Jack Butland had been tipped for a senior call-up, but he is named in the England Under-21 squad for Wednesday's game against Wales in Derby.
Ravel Morrison and James Ward-Prowse have also been named in that squad by coach Gareth Southgate.
Hodgson has challenged Shaw to provide competition to established left-backs Ashley Cole and Leighton Baines for a place in his World Cup squad having performed well for Saints of late.
"I think everyone who has watched him play recently will not deny that he deserves a place in a large squad like this," he said.
"He has played extremely well and is an exciting talent. I think it was the right moment to invite him along. He is a player in a position where we are well off but he wants to compete with the other two for a place on the plane to Brazil."
With Jagielka absent, Cardiff skipper Caulker was called upon on after Hodgson admitted he was unable to select injured Manchester United defender Phil Jones.
"We have asked Steve Caulker to come in as well," he said.
"He wasn't in my original list of 30, Jagielka was and so was Jones until I found out it is a few weeks until he returns. It is not the first time it has happened to us."
Liverpool winger Sterling returns to the squad alongside team-mates Glen Johnson, Steven Gerrard, Jordan Henderson and Daniel Sturridge, with Hodgson impressed with the Reds' current form.
"They [Liverpool] have been fantastic," he said.
"They have played brilliantly well, their pressuring has been very, very good and they have made life difficult for the opposition.
"They have been quick out of the blocks and when they have won the ball they have been devastating.
"Raheem was with us for one of the qualifying games we played last year, he is a player I know from Liverpool but after bursting into the team he went away for a while but he is back now better than ever.
"They start afresh now they are with England, hopefully they will bring their confidence with them but (club and international football) are two different things."
With the likes of Carroll, Ashley Young and in-form Everton midfielder Gareth Barry missing out on his squad, Hodgson was quick to rebuff claims no players could work their way into his thinking before the World Cup.
When asked if other players had run out of chances, Hodgson said: "No. That is the message I'm keen to put over.
"It would be foolish in March to give a definitive 30 man-squad. Anyone I might decide I want to take if they are not in this 30, I am entitled to do that.
"Andy Carroll has hardly played but we will be keeping an eye on him.
"Gareth has not been with us in the two years but he is playing well at the moment and I wouldn't be averse to calling him up if I thought he had a place in the team."
Likewise, Hodgson stressed those players named in his squad to face Denmark should not rest on their laurels.
"I'm not prepared to give that guarantee," he added.
"Anyone who thinks that may find themselves disillusioned. There is still plenty of football to be played. The period now between March 5 and May 11 is a very, very busy period. There are quite a few weeks where people will be playing three times.
"I think I have chosen a strong 30-man squad here, having a 30-man squad is good. I shall just wait and see and on a weekly basis maybe have to reassess."
England squad to face Denmark at Wembley on Wednesday, March 5:
Fraser Forster (Celtic), Ben Foster (West Brom), Joe Hart (Manchester City), John Ruddy (Norwich); Leighton Baines (Everton), Gary Cahill (Chelsea), Steven Caulker (Cardiff), Ashley Cole (Chelsea), Glen Johnson (Liverpool), Luke Shaw (Southampton), Chris Smalling (Manchester United), Kyle Walker (Tottenham); Ross Barkley (Everton), Michael Carrick (Manchester United), Tom Cleverley (Manchester United), Steven Gerrard (Liverpool), Jordan Henderson (Liverpool), Adam Lallana (Southampton), Frank Lampard (Chelsea), James Milner (Manchester City), Alex Oxlade-Chamberlain (Arsenal), Raheem Sterling (Liverpool), Andros Townsend (Tottenham), Jack Wilshere (Arsenal); Jermain Defoe (Toronto FC), Rickie Lambert (Southampton), Jay Rodriguez (Southampton), Wayne Rooney (Manchester United), Daniel Sturridge (Liverpool), Danny Welbeck (Manchester United).